Français
Fast structure and positional ortholog searching and viral metagenome assembly
Multi angle
Authors : Söding, Johannes (Author of the conference)
CIRM (Publisher )
CIRM (Publisher )
Loading the player...
|
Abstract :
I will give an update on Foldseek, which can perform structural similarity searches and alignment through the Uniprot50 and MGnify/ESM30 database of 95M structures in a few seconds on a single core, at a sensitivity similar to TMalign (search.foldseek.com). At its core is the 3Di structural alphabet that we learned using a discrete variational autoencoder. I will also present SpaceDust, a tool for fast sequence- and structure-based searches of clusters of 'positional orthologs' between genomes, as well as PenguiN, our new strain-resolved viral metagenome assembler.
MSC Codes : |
Information on the Video
Film maker : Hennenfent, GuillaumeLanguage : English Available date : 03/04/2023 Conference Date : 21/03/2023 Subseries : Research talks arXiv category : Quantitative Biology Mathematical Area(s) : Numerical Analysis & Scientific Computing ; Computer Science ; Probability & Statistics Format : MP4 (.mp4) - HD Video Time : 00:29:23 Targeted Audience : Researchers ; Graduate Students ; Doctoral Students, Post-Doctoral Students Download : https://videos.cirm-math.fr/2023-03-21_Soding.mp4 
|
Information on the Event
Event Title : Interplay between AI and mathematical modelling in the post-structural genomics era / Interaction entre l'IA et la modélisation mathématique à l'ère post-génomique structuraleEvent Organizers : Fidelis, Krzysztof ; Grudinin, Sergei ; Laine, Elodie Dates : 20/03/2023 - 24/03/2023 Event Year : 2023 Event URL : https://conferences.cirm-math.fr/2767.html
Citation Data
DOI : 10.24350/CIRM.V.20020603Cite this video as: Söding, Johannes (2023). Fast structure and positional ortholog searching and viral metagenome assembly. CIRM. Audiovisual resource. doi:10.24350/CIRM.V.20020603 URI : http://dx.doi.org/10.24350/CIRM.V.20020603 |
See Also
- [Multi angle] The unexplained effectiveness of multilingual NLP / Author of the conference Yvon, François.
- [Multi angle] Artificial Intelligence captures language of life written in proteins / Author of the conference Rost, Burkhard.
- [Multi angle] Evolutionary conservation of RNA structure / Author of the conference Rivas, Elena.
- [Multi angle] Topsy-Turvy: integrating a global view into sequence-based protein-protein interaction prediction / Author of the conference Cowen, Lenore.
Bibliography
Imagette Video
