Résumé : In this talk I will discuss about the unirationality of the Hurwitz spaces $H_{g,d}$ parametrizing d-sheeted branched simple covers of the projective line by smooth curves of genus $g$. I will summarize what is already known and formulate some questions and speculations on the general behaviour. I will then present a proof of the unirationality of $H_{12,8}$ and $H_{13,7}$, obtained via liaison and matrix factorizations. This is part of two joint works with Frank-Olaf Schreyer.