English
Multi-level mathematical models for cell migration in dense fibrous environments
Multi angle
Auteurs : Preziosi, Luigi (Auteur de la conférence)
CIRM (Editeur )
65C20 - Models (numerical methods)
92C17 - Cell movement (chemotaxis, etc.)
92C37 - Cell biology
92C50 - Medical applications of mathematical biology
92C42 - Systems biology, networks
CIRM (Editeur )
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Résumé :
Cell-extracellular matrix interaction and the mechanical properties of cell nucleus have been demonstrated to play a fundamental role in cell movement across fibre networks and micro-channels and then in the spread of cancer metastases. The lectures will be aimed at presenting several mathematical models dealing with such a problem, starting from modelling cell adhesion mechanics to the inclusion of influence of nucleus stiffness in the motion of cells, through continuum mechanics, kinetic models and individual cell-based models.
Codes MSC : 65C20 - Models (numerical methods)
92C17 - Cell movement (chemotaxis, etc.)
92C37 - Cell biology
92C50 - Medical applications of mathematical biology
92C42 - Systems biology, networks
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Informations sur la Vidéo
Réalisateur : Hennenfent, GuillaumeLangue : Anglais Date de Publication : 26/07/2018 Date de Captation : 18/07/2018 Collection : Ecoles de recherche Sous Collection : Research School Catégorie arXiv : Quantitative Biology ; Mathematical Physics Domaine(s) : Analyse Numérique & Calcul Formel ; Mathématiques pour les Sciences & Technologies Format : MP4 (.mp4) - HD Durée : 01:22:56 Audience : Chercheurs ; Etudiants Science Cycle 2 Download : https://videos.cirm-math.fr/2018-07-18_Preziosi.mp4 
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Informations sur la Rencontre
Nom de la Rencontre : CEMRACS - Summer school: Numerical and mathematical modeling for biological and medical applications: deterministic, probabilistic and statistical descriptions / CEMRACS - École d'été : Modélisation numérique et mathématique pour la biologie et la médecine : descriptions déterministes, probabilistes et statistiquesOrganisateurs de la Rencontre : Calvez, Vincent ; Grandmont, Céline ; Löcherbach, Eva ; Poignard, Clair ; Ribot, Nathalie ; Vauchelet, Nicolas Dates : 16/07/2018 - 24/08/2018 Année de la rencontre : 2018 URL de la Rencontre : https://conferences.cirm-math.fr/1834.html
Données de citation
DOI : 10.24350/CIRM.V.19421703Citer cette vidéo: Preziosi, Luigi (2018). Multi-level mathematical models for cell migration in dense fibrous environments. CIRM. Audiovisual resource. doi:10.24350/CIRM.V.19421703 URI : http://dx.doi.org/10.24350/CIRM.V.19421703 |
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Bibliographie
- Butcher, D.T., Alliston, T., Weaver, V.M. (2009). A tense situation: forcing tumour progression. Nature Reviews Cancer, 9, 108-122 - http://dx.doi.org/10.1038/nrc2544
- Guilak, F., Cohen, D.M., Estes, B.T., Gimble, J.M., Liedtke, W., & Chen, C.S. (2009). Control of stem cell fate by physical interactions with the extracellular matrix. Cell Stem Cell, 5, 17-26 - https://doi.org/10.1016/j.stem.2009.06.016
- Ingber, D.E. (2003). Mechanobiology and diseases of mechanotransduction. Annals of medicine, 35(8), 564-577 - https://doi.org/10.1080/07853890310016333
- Kassa, L., Erler, J.T., Dembo, M., & Weaver, V.M. (2007). Mammary epithelial cell: Influence of extracellular matrix composition and organization during development and tumorigenesis. The International Journal of Biochemistry & Cell Biology, 39(11), 1987-1994 - https://doi.org/10.1016/j.biocel.2007.06.025
- Lindvall, O., & Kokaia, Z. (2010). Stem cells in human neurodegenerative disorders — time for clinical translation? The Journal of Clinical Investigation, 120(1), 29-40 - https://dx.doi.org/10.1172%2FJCI40543
- Lindvall, O., & Kokaia, Z. (2006). Stem cells for the treatment of neurological disorders. Nature, 441, 1094-1096 - http://dx.doi.org/10.1038/nature04960
- Sun, Y., Chen, C.S., & Fu, J. (2012). Forcing stem cells to behave: a biophysical perspective of the cellular microenvironment. Annual Review of Biophysics, 41, 519-542 - https://doi.org/10.1146/annurev-biophys-042910-155306
- Tosin, A., & Preziosi, L. (2010). Multiphase modeling of tumor growth with matrix remodeling and fibrosis. Mathematical and Computer Modelling, 52(7–8), 969-976 - https://doi.org/10.1016/j.mcm.2010.01.015
