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General epidemiological models: law of large numbers and contact tracing

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Auteurs : Schertzer, Emmanuel (Auteur de la Conférence)
CIRM (Editeur )

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Résumé : We study a class of individual-based, fixed-population size epidemic models under general assumptions, e.g., heterogeneous contact rates encapsulating changes in behavior and/or enforcement of control measures. We show that the large-population dynamics are deterministic and relate to the Kermack-McKendrick PDE. Our assumptions are minimalistic in the sense that the only important requirement is that the basic reproduction number of the epidemic $R_0$ be finite, and allow us to tackle both Markovian and non-Markovian dynamics. The novelty of our approach is to study the "infection graph" of the population. We show local convergence of this random graph to a Poisson (Galton-Watson) marked tree, recovering Markovian backward-in-time dynamics in the limit as we trace back the transmission chain leading to a focal infection. This effectively models the process of contact tracing in a large population. It is expressed in terms of the Doob h-transform of a certain renewal process encoding the time of infection along the chain. Our results provide a mathematical formulation relating a fundamental epidemiological quantity, the generation time distribution, to the successive time of infections along this transmission chain.

Keywords : General epidemiological models; contact tracing; McKendrick-Von Foerster PDE

Codes MSC :
60F17 - Functional limit theorems; invariance principles
60G20 - Generalized stochastic processes
60J80 - Branching processes (Galton-Watson, birth-and-death, etc.)

    Informations sur la Vidéo

    Réalisateur : Hennenfent, Guillaume
    Langue : Anglais
    Date de publication : 02/08/2021
    Date de captation : 28/06/2021
    Sous collection : Research talks
    arXiv category : Probability ; Quantitative Biology
    Domaine : Probability & Statistics
    Format : MP4 (.mp4) - HD
    Durée : 00:49:30
    Audience : Researchers
    Download : https://videos.cirm-math.fr/2021-06-28_Schertzer.mp4

Informations sur la Rencontre

Nom de la rencontre : 5th Workshop Probability and Evolution / 5ème rencontre Probabilités et évolution
Organisateurs de la rencontre : Lambert, Amaury ; Pfaffelhuber, Peter
Dates : 28/06/2021 - 02/07/2021
Année de la rencontre : 2021
URL Congrès : https://conferences.cirm-math.fr/2307.html

Données de citation

DOI : 10.24350/CIRM.V.19773103
Citer cette vidéo: Schertzer, Emmanuel (2021). General epidemiological models: law of large numbers and contact tracing. CIRM. Audiovisual resource. doi:10.24350/CIRM.V.19773103
URI : http://dx.doi.org/10.24350/CIRM.V.19773103

Voir aussi

Bibliographie

  • DUCHAMPS, Jean-Jil, FOUTEL-RODIER, Félix, et SCHERTZER, Emmanuel. General epidemiological models: Law of large numbers and contact tracing. arXiv preprint arXiv:2106.13135, 2021. - https://arxiv.org/abs/2106.13135



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