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Direct and inverse biomechanical modeling of the heart
Multi angle
Authors : Chapelle, Dominique (Author of the conference)
CIRM (Publisher )
92C10 - Biomechanics
92C55 - Biomedical imaging and signal processing, tomography
74H15 - Numerical approximation of solutions
CIRM (Publisher )
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Abstract :
The heart undergoes some highly complex multi-scale multi-physics phenomena that must be accounted for in order to adequately model the biomechanical behavior of the complete organ. In this respect, a major focus of our work has been on formulating modeling ingredients that satisfy the most crucial thermomechanical requirements - in particular as regards energy balances - throughout the various forms of physical and scale-related couplings. This has led to a "beating heart" model for which some experimental and clinical validations have already been obtained. Concurrently, with the objective of building "patient-specific" heart models, we have investigated some original approaches inspired from data assimilation concepts to benefit from the available clinical data, with a particular concern for medical imaging. By combining the two fundamental sources of information represented by the model and the data, we are able to extract some most valuable quantitative knowledge on a given heart, e.g. as regards some uncertain constitutive parameter values characterizing a possible pathology, with important perspectives in diagnosis assistance. In addition, once the overall uncertainty has been adequately controlled via this adjustment process, the model can be expected to become "predictive", hence should provide clinically-relevant quantitative information, both in the current state of the patient and under various scenarii of future evolutions, such as for therapy planning.
MSC Codes : 92C10 - Biomechanics
92C55 - Biomedical imaging and signal processing, tomography
74H15 - Numerical approximation of solutions
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Information on the Video
Film maker : Hennenfent, GuillaumeLanguage : English Available date : 10/08/16 Conference Date : 10/08/16 Subseries : Research talks arXiv category : Numerical Analysis ; Quantitative Biology Mathematical Area(s) : Numerical Analysis & Scientific Computing ; Mathematical Physics ; Mathematics in Science & Technology Format : MP4 (.mp4) - HD Video Time : 00:57:49 Targeted Audience : Researchers Download : https://videos.cirm-math.fr/2016-08-10_Chapelle.mp4 
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Information on the Event
Event Title : CEMRACS: Numerical challenges in parallel scientific computing / CEMRACS : Défis numériques en calcul scientifique parallèleEvent Organizers : Grigori, Laura ; Japhet, Caroline ; Moireau, Philippe ; Parnaudeau, Philippe Dates : 18/07/16 - 26/08/16 Event Year : 2016 Event URL : http://conferences.cirm-math.fr/1430.html
Citation Data
DOI : 10.24350/CIRM.V.19028603Cite this video as: Chapelle, Dominique (2016). Direct and inverse biomechanical modeling of the heart. CIRM. Audiovisual resource. doi:10.24350/CIRM.V.19028603 URI : http://dx.doi.org/10.24350/CIRM.V.19028603 |
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