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Every patient deserves their own equation: Sex, drugs and radiomics of brain Cancer
Virtualconference
Authors : Swanson, Kristin (Author of the conference)
CIRM (Publisher )
92C50 - Medical applications of mathematical biology
CIRM (Publisher )
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Abstract :
Glioblastoma are notoriously aggressive, malignant primary brain tumors that have variable response to treatment. This presentation will focus on the integrative role of 1) biological sex-differences, 2) heterogeneity in drug-delivery and 3) intra-tumoral molecular diversity (revealed by radiomics) in capturing and predicting this variable response to treatment. Specifically, I will highlight burgeoning insights into sex differences in tumor incidence, outcomes, propensity and response to therapy. I will further, quantify the degree to which heterogeneity in drug delivery, even for drugs that are able to bypass the blood-brain barrier, contributes to differences in treatment response. Lastly, I will propose an integrative role for spatially resolved MRI-based radiomics models to reveal the intra-tumoral biological heterogeneity that can be used to guide treatment targeting and management.
Keywords : mathematical oncology
MSC Codes : Keywords : mathematical oncology
92C50 - Medical applications of mathematical biology
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Information on the Video
Film maker : Hennenfent, GuillaumeLanguage : English Available date : 01/07/2022 Conference Date : 07/06/2022 Subseries : Research School arXiv category : Quantitative Biology Mathematical Area(s) : Numerical Analysis & Scientific Computing ; Computer Science ; Control Theory & Optimization ; PDE Format : MP4 (.mp4) - HD Video Time : 00:34:33 Targeted Audience : Researchers ; Graduate Students ; Doctoral Students, Post-Doctoral Students Download : https://videos.cirm-math.fr/2022-06-07_Swanson.mp4 
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Information on the Event
Event Title : Dynamics and Statistics of Cancer Evolution : Applying Mathematics to Experimental and Clinical Data / Evolution tumorale, dynamique et statistiques: mathématiques pour données cliniques & expérimentalesEvent Organizers : Curtius, Kathleen ; Huang, Weini ; Martinez, Pierre ; Werner, Benjamin ; Williams, Marc Dates : 06/06/2022 - 10/06/2022 Event Year : 2022 Event URL : https://conferences.cirm-math.fr/2409.html
Citation Data
DOI : 10.24350/CIRM.V.19931803Cite this video as: Swanson, Kristin (2022). Every patient deserves their own equation: Sex, drugs and radiomics of brain Cancer. CIRM. Audiovisual resource. doi:10.24350/CIRM.V.19931803 URI : http://dx.doi.org/10.24350/CIRM.V.19931803 |
See Also
- [Multi angle] Evolutionary dynamics of drug resistance in cancer / Author of the conference Wodarz, Dominik.
- [Virtualconference] Incorporating ecological epistasis into evolutionary control of cancer / Author of the conference Scott, Jake.
- [Multi angle] Evolutionary dynamics of cancer driven by the random segregation of extra-chromosomal DNA / Author of the conference Huang, Weini ; Author of the conference Werner, Benjamin.
- [Multi angle] Evolutionary therapy / Author of the conference Anderson, R.A. Alexander.
Bibliography
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