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Near-criticality in mathematical models of epidemics - Luczak, Malwina (Auteur de la Conférence) | CIRM H

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In an epidemic model, the basic reproduction number $ R_{0}$ is a function of the parameters (such as infection rate) measuring disease infectivity. In a large population, if $ R_{0}> 1$, then the disease can spread and infect much of the population (supercritical epidemic); if $ R_{0}< 1$, then the disease will die out quickly (subcritical epidemic), with only few individuals infected.
For many epidemics, the dynamics are such that $ R_{0}$ can cross the threshold from supercritical to subcritical (for instance, due to control measures such as vaccination) or from subcritical to supercritical (for instance, due to a virus mutation making it easier for it to infect hosts). Therefore, near-criticality can be thought of as a paradigm for disease emergence and eradication, and understanding near-critical phenomena is a key epidemiological challenge.
In this talk, we explore near-criticality in the context of some simple models of SIS (susceptible-infective-susceptible) epidemics in large homogeneous populations.[-]
In an epidemic model, the basic reproduction number $ R_{0}$ is a function of the parameters (such as infection rate) measuring disease infectivity. In a large population, if $ R_{0}> 1$, then the disease can spread and infect much of the population (supercritical epidemic); if $ R_{0}< 1$, then the disease will die out quickly (subcritical epidemic), with only few individuals infected.
For many epidemics, the dynamics are such that $ R_{0}$ can ...[+]

92D30 ; 05C80 ; 92D25 ; 60J28

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